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EZHI-14BK Human Insulin ELISA- Space Saver (Bulk) Packaging

This Human Insulin ELISA is used to measure & quantify insulin levels in Metabolism & Endocrine research.

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EZHI-14BK
96-well strip plate  
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      Overview

      Replacement Information
      Description
      Catalogue NumberEZHI-14BK
      DescriptionHuman Insulin ELISA- Space Saver (Bulk) Packaging
      Background InformationInsulin, a 5.8 kDa hormone, is secreted by the islet beta cells in the pancreas.
      References
      Product Information
      Detection methodFluorescent Colorimetric
      Precision, %
      • Inter-assay: 9.1–11.4
      • Intra-assay: 4.6–7.0
      Quality LevelMQ200
      Applications
      ApplicationThis Human Insulin ELISA is used to measure & quantify insulin levels in Metabolism & Endocrine research.
      Key Applications
      • ELISA
      Application Notes2 hour assay, room temperature Sample ≤ 20 μL serum, plasma, or tissue culture medium
      Biological Information
      Species Reactivity
      • Human
      Analytes Available
      • Insulin
      Entrez Gene Number
      Entrez Gene SummaryAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.
      Gene Symbol
      • INS
      • proinsulin
      • insulin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      SIZE: 110 amino acids; 11981 Da
      SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
      SUBCELLULAR LOCATION: Secreted.
      DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
      SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.
      Accuracy
      • 76–103%
      Physicochemical Information
      Linearity of Dilution96–112%
      Standard Curve Range
      • 2–200 μU/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • For research use only. Not for use in diagnostic procedures.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      EZHI-14BK 04053252674211

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