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475995 InhibitorSelect™ mTOR Signaling Regulators Panel - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
475995
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      A panel containing 17 potent and selective small molecule regulators that is useful for the study of mTOR signaling: 1 mg of Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (Cat. No. 124018), 10 mg of Akt Inhibitor XVI, AT7867 (Cat. No. 124033), 1 mg of AMPK Inhibitor, Compound C (Cat. No. 171260), 10 mg of bpV(phen) (Cat. No. 203695), 5 mg of Compound 401 (Cat. No. 234501), 1 mg of H-89, Dihydrochloride (Cat. No. 371963), 5 mg of mTOR Inhibitor III, PP242 (Cat. No. 475988), 5 mg of mTOR Inhibitor IV, Ku-63794 (Cat. No. 475990), 5 mg of PDK1 Inhibitor II, BX-517 (Cat. No. 521276), 1 mg of PI-103 (Cat. No. 528100), 1 mg of PI 3-Kβ Inhibitor VI, TGX-221 (Cat. No. 528113), 5 mg of PTK/PI 3-K/mTOR Inhibitor, PP121 (Cat. No. 529584), 1 mg of Rapamycin (Cat. No. 553210), 10 mg of S6K1 Inhibitor, PF-4708671 (Cat. No. 559273), 10 mg of SHIP1 Inhibitor, 3AC (Cat. No. 565835), 10 mg of SHIP2 Inhibitor, AS1938909 (Cat. No. 565840), 1 mg of U0126 (Cat. No. 662005). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817). Supplied with a data sheet.
      Catalogue Number475995
      Brand Family Calbiochem®
      References
      ReferencesZoncu, R., et al. 2011. Nat. Rev. Mol. Cell Biol. 12, 21.
      Foster, K.G. and Fingar, D.C., 2010. J. Biol. Chem. 285, 14071.
      Albert, S., et al. 2010. Expert Opin. Investing Drugs 19, 919.
      Hoeffer, C.A. and Klann, E., 2010. Trends Neurosci. 33, 67.
      Laplante, M. and Sabatini, D.M., 2009. J. Cell Sci. 122, 3589.
      Meric-Bernstam, F. and Gonzalez-Angulo, A.M., 2009. J. Clin. Oncol. 27, 2278.
      Faivre, S., et al. 2006. Nat. Rev. Drug Discov. 5, 671.
      Product Information
      FormSolid
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      475995 0

      Documentation

      References

      Reference overview
      Zoncu, R., et al. 2011. Nat. Rev. Mol. Cell Biol. 12, 21.
      Foster, K.G. and Fingar, D.C., 2010. J. Biol. Chem. 285, 14071.
      Albert, S., et al. 2010. Expert Opin. Investing Drugs 19, 919.
      Hoeffer, C.A. and Klann, E., 2010. Trends Neurosci. 33, 67.
      Laplante, M. and Sabatini, D.M., 2009. J. Cell Sci. 122, 3589.
      Meric-Bernstam, F. and Gonzalez-Angulo, A.M., 2009. J. Clin. Oncol. 27, 2278.
      Faivre, S., et al. 2006. Nat. Rev. Drug Discov. 5, 671.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-June-2013 JSW
      DescriptionA panel containing 17 potent and selective small molecule regulators that is useful for the study of mTOR signaling. This panel contains the following inhibitors as well as 15 ml anhydrous DMSO for reconstitution:
      FormSolid
      Intert gas (Yes/No) Packaged under inert gas
      SolubilityDMSO (supplied). Please refer to information provided on the CD for reconstitution information of individual inhibitors.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesZoncu, R., et al. 2011. Nat. Rev. Mol. Cell Biol. 12, 21.
      Foster, K.G. and Fingar, D.C., 2010. J. Biol. Chem. 285, 14071.
      Albert, S., et al. 2010. Expert Opin. Investing Drugs 19, 919.
      Hoeffer, C.A. and Klann, E., 2010. Trends Neurosci. 33, 67.
      Laplante, M. and Sabatini, D.M., 2009. J. Cell Sci. 122, 3589.
      Meric-Bernstam, F. and Gonzalez-Angulo, A.M., 2009. J. Clin. Oncol. 27, 2278.
      Faivre, S., et al. 2006. Nat. Rev. Drug Discov. 5, 671.