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407952 Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem

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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      56092-82-1C₄₁H₇₀O₉ · Ca
      Description
      Overview

      This product has been discontinued.



      Useful in cell activation experiments when calcium dose-response data are not required. Also available as a 10 mM solution in DMSO (Cat. No. 407953).

      Catalogue Number407952
      Brand Family Calbiochem®
      References
      ReferencesDupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
      Lee, H.C. 1993. J. Biol. Chem. 268, 293.
      Product Information
      CAS number56092-82-1
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₄₁H₇₀O₉ · Ca
      Chemical formulaC₄₁H₇₀O₉ · Ca
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetUseful in cell activation experiments
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSNO0650000
      Safety Information
      R PhraseR: 22

      Harmful if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 year at 4°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      407952 0

      Documentation

      Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      407952

      References

      Reference overview
      Dupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
      Lee, H.C. 1993. J. Biol. Chem. 268, 293.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-February-2010 RFH
      DescriptionHighly specific for divalent cations (Ca2+ > Mg2+ >> Sr2+ = Ba2+) and more effective than antibiotic A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5, with intense UV absorption. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes. Induces apoptotic neuronal degeneration in embryonic cortical neurons. Also induces cell cycle arrest in the G1 interval of mature Burkitt lymphoma cell lines. Often used in cell activation experiments when calcium dose-response data is not required.
      FormWhite to off-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number56092-82-1
      RTECSNO0650000
      Chemical formulaC₄₁H₇₀O₉ · Ca
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (100 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 year at 4°C.
      Toxicity Harmful
      ReferencesDupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
      Lee, H.C. 1993. J. Biol. Chem. 268, 293.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores