371956 Iso-H-7, Dihydrochloride
Recommended Products
Overview
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| Description | |
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| Overview | This product has been discontinued. We are currently only offering the parent inhibitor, H-7, Dihydrochloride (Cat. No. 371955) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information. Cell permable and less potent than H-7 in inhibiting rat brain protein kinase C isoforms (IC50 = 50 µM). Also inhibits cyclic-nucleotide-dependent protein kinases. |
| Catalogue Number | 371956 |
| Brand Family | Calbiochem® |
| Synonyms | 1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, 2HCl |
| References | |
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| References | Quick, J., et al. 1992. Biochem. Biophys. Res. Commun. 187, 657. |
| Product Information | |
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| CAS number | 140663-38-3 |
| Form | Faint yellow lyophilized solid |
| Hill Formula | C₁₄H₁₇N₃O₂S · 2HCl |
| Chemical formula | C₁₄H₁₇N₃O₂S · 2HCl |
| Structure formula Image | |
| Applications |
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| Biological Information | |
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| Primary Target | PKC isoforms |
| Primary Target IC<sub>50</sub> | 50 µM |
| Purity | ≥98% by TLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalog Number | GTIN |
| 371956 | 0 |
Documentation
References
| Reference overview |
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| Quick, J., et al. 1992. Biochem. Biophys. Res. Commun. 187, 657. |
Brochure
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| PKC Pathway Poster PDF ( 676 KB ) |