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420311 Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem

An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Kamycin

Primary Target: protein biosynthesis
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      25389-94-0C₁₈H₃₆N₄O₁₁ · H₂SO₄
      Description
      OverviewContains more than 98% kanamycin A. An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
      Potency: ≥750 µg/mg
      Catalogue Number420311
      Brand Family Calbiochem®
      SynonymsKamycin
      References
      ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
      Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
      Cardon, G.H., et al. 1993. Plant J. 3, 773.
      Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
      Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
      Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
      Umezawa, S., et al. 1968. J. Antibiot. 21, 367.
      Product Information
      CAS number25389-94-0
      FormWhite to off-white solid
      Hill FormulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
      Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetprotein biosynthesis
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSNZ3225030
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      420311 0

      Documentation

      Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      420311

      References

      Reference overview
      Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
      Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
      Cardon, G.H., et al. 1993. Plant J. 3, 773.
      Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
      Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
      Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
      Umezawa, S., et al. 1968. J. Antibiot. 21, 367.

      Brochure

      Title
      Antibiotics Profiler
      Bulk packaging
      Overnight Express Autoinduction Systems

      Citations

      Title
    • Thomas S. Lendvay, et al. (2007) Compensatory paracrine mechanisms that define the urothelial response to injury in partial bladder outlet obstruction. American Journal of Physiology: Renal 293, F1147-F1156.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision24-September-2010 JSW
      SynonymsKamycin
      DescriptionContains more than 98% kanamycin A. An aminoglycoside antibiotic affective against gram-positive and gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 70S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
      FormWhite to off-white solid
      CAS number25389-94-0
      RTECSNZ3225030
      Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
      Structure formulaStructure formula
      SolubilityH₂O (10 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Merck USA index14, 5281
      ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
      Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
      Cardon, G.H., et al. 1993. Plant J. 3, 773.
      Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
      Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
      Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
      Umezawa, S., et al. 1968. J. Antibiot. 21, 367.
      Citation
    • Thomas S. Lendvay, et al. (2007) Compensatory paracrine mechanisms that define the urothelial response to injury in partial bladder outlet obstruction. American Journal of Physiology: Renal 293, F1147-F1156.
      		•

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Protein Synthesis Inhibitors
      Life Science Research > Cell Culture and Systems > Antibiotics & Selection Agents
      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antimicrobial Agents