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454565 Methyl Arachidonyl Fluorophosphonate - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: MAFP, cPLA2α Inhibitor III

Primary Target: calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₂₁H₃₆FO₂P
      Description
      Overview

      This product has been discontinued.



      A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2) but not of secretory PLA2.
      Catalogue Number454565
      Brand Family Calbiochem®
      SynonymsMAFP, cPLA2α Inhibitor III
      References
      ReferencesBalsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
      Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.
      Product Information
      ATP CompetitiveN
      FormLiquid
      FormulationIn methyl acetate.
      Hill FormulaC₂₁H₃₆FO₂P
      Chemical formulaC₂₁H₃₆FO₂P
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcalcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsPrior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      454565 0

      Documentation

      Methyl Arachidonyl Fluorophosphonate - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Methyl Arachidonyl Fluorophosphonate - Calbiochem Certificates of Analysis

      TitleLot Number
      454565

      References

      Reference overview
      Balsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
      Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-August-2008 RFH
      SynonymsMAFP, cPLA2α Inhibitor III
      DescriptionA selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2) but not secretory PLA2.
      FormLiquid
      FormulationIn methyl acetate.
      Chemical formulaC₂₁H₃₆FO₂P
      Structure formulaStructure formula
      Purity≥98% by TLC
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsPrior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.
      Toxicity Standard Handling
      ReferencesBalsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
      Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.