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MAC507-100UG Mouse Anti-Llama IgG2 Antibody, clone 19D8

Mouse Anti-Llama IgG2, clone 19D8, Cat. No. MAC507, is a mouse monoclonal antibody that detects Llama IgG2 and is tested for use in ELISA, Immunoaffinity, Purification, and Western Blotting.

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MAC507-100UG
100 μg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberMAC507-100UG
      DescriptionMouse Anti-Llama IgG2 Antibody, clone 19D8
      Alternate Names
      • IgG2 HCAb
      • IgG2 Nanobody
      Background InformationLlama, camels, and alpacas are camelids that produce normal IgG1 like antibodies and also functional IgG isotypes that do not incorporate light chains and possess only heavy chains. These heavy-chain antibodies may constitute about 50% of the IgG in llama serum and as much as 75% of the IgG in camel serum. By virtue of their smaller size they exhibit better bio-distribution, tissue penetration, and monomeric behavior. IgG2 consists of dimers of short heavy chains, which are characterized by a normal Fc region without a CH1 domain. Although it lacks the CH1 region, it still retains an antigen binding domain called the VHH region. Clone 19D8 is shown to specifically bind to three discrete IgG2 isotypes, designated as a, b, and c, in Llama. (Ref.: Daley, LP., et al. (2005). Clin. Diag. Lab. Immunol. 12(4); 380-386).
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ200
      Applications
      ApplicationMouse Anti-Llama IgG2, clone 19D8, Cat. No. MAC507, is a mouse monoclonal antibody that detects Llama IgG2 and is tested for use in ELISA, Immunoaffinity, Purification, and Western Blotting.
      Key Applications
      • Western Blotting
      • ELISA
      • Immunoaffinity Purification
      Application NotesTested Applications

      ELISA Analysis: A representative lot detected Mouse Anti-Llama IgG2 in ELISA applications (Daley, L.P., et. al. (2005). Clin Diagn Lab Immunol. 12(3):380-6; Daley-Bauer, L.P., et. al. (2010). Clin Vaccine Immunol. 17(12):2007-15).

      Immunoaffinity Purification: A representative lot was used in Immunoaffinity Purification applications (Daley, L.P., et. al. (2005). Clin Diagn Lab Immunol. 12(3):380-6; Daley-Bauer, L.P., et. al. (2010). Clin Vaccine Immunol. 17(12):2007-15).

      Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user
      Biological Information
      ImmunogenPurified Llama serum IgG2.
      EpitopeUnknown
      Clone19D8
      Concentration1.0 mg/mL. Please refer to guidance on suggested starting dilutions and/or titers per application and sample type.
      HostMouse
      SpecificityClone 19D8 is a mouse monoclonal antibody that detects Llama IgG2.
      Species Reactivity
      • Mammals
      Species Reactivity NoteLlama.
      Antibody TypeMonoclonal Antibody
      Purification MethodProtein G purified
      UniProt Number
      Molecular Weight~45 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting with Llama IgG2.

      Western Blotting Analysis (WB): A 1:1,000 dilution of this antibody detected Llama IgG2, but not IgG1 or IgG3.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsRecommend storage at +2°C to +8°C. For long term storage antibodies can be kept at -20°C . Avoid repeated freeze-thaws.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MAC507-100UG 04065266298420

      Documentation

      Mouse Anti-Llama IgG2 Antibody, clone 19D8 SDS

      Title

      Safety Data Sheet (SDS) 

      Mouse Anti-Llama IgG2 Antibody, clone 19D8 Certificates of Analysis

      TitleLot Number
      Mouse Anti-Llama IgG2, clone 19D8 - 3899616 3899616
      Mouse Anti-Llama IgG2, clone 19D8 - 3985011 3985011
      Mouse Anti-Llama IgG2, clone 19D8 - 4010113 4010113
      Mouse Anti-Llama IgG2, clone 19D8 - 4026472 4026472
      Mouse Anti-Llama IgG2, clone 19D8 - 4035512 4035512
      Mouse Anti-Llama IgG2, clone 19D8 - 4035833 4035833
      Mouse Anti-Llama IgG2, clone 19D8 - 4070809 4070809
      Mouse Anti-Llama IgG2, clone 19D8 - 4097753 4097753
      Mouse Anti-Llama IgG2, clone 19D8 - 4156842 4156842
      Mouse Anti-Llama IgG2, clone 19D8 - Q3705922 Q3705922