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GF308 NT-3 Protein, Human Recombinant Animal Free

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GF308
10 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      SourcePurity
      E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      Description
      Catalogue NumberGF308
      DescriptionNT-3 Protein, Human Recombinant Animal Free
      Alternate Names
      • NT3
      • Neurotrophin 3
      • HDNF
      • Nerve growth factor 2
      • Neurotrophic factor
      Background InformationNeurotrophin3 (NT3) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT3, and NT4/5. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues).Human and Mouse NT-3 sequences are identical.
      References
      Product Information
      Formulation
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization. Product is presented in .
      Quality LevelMQ100
      Applications
      ApplicationRecombinant animal free human NT-3 is manufactured using all non-animal reagents.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      SourceE. coli
      Cross ReactivityNone
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      GF308 04053252691317

      Documentation

      NT-3 Protein, Human Recombinant Animal Free Certificates of Analysis

      TitleLot Number
      Recombinant Animal Free Human NT-3 - 2137057 2137057
      Recombinant Animal Free Human NT-3 - 2390572 2390572
      Recombinant Animal Free -2594439 2594439
      Recombinant Animal Free -2676709 2676709
      Recombinant Animal Free -2687813 2687813
      Recombinant Animal Free -2714436 2714436
      Recombinant Animal Free -2765738 2765738
      Recombinant Animal Free -2776261 2776261
      Recombinant Animal Free -2801977 2801977
      Recombinant Animal Free Human NT-3 2467141

      Related Products & Applications

      Product Families

      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors