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480066 Necrostatin-1, Inactive Control - CAS 64419-92-7 - Calbiochem

Overview

Key Specifications Table

CAS #Empirical Formula
64419-92-7C₁₂H₁₁N₃OS

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480066-5MG
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      Description
      OverviewA cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) that is devoid of anti-necroptotic properties and serves as a suitable inactive control.

      Note: This inactive inhibitor of necrosis should not be used in high concentration.
      Catalogue Number480066
      Brand Family Calbiochem®
      Synonyms5-(Indol-3-ylmethyl)-2-thiohydantoin, Nec-1i
      References
      ReferencesTakahashi et al. 2012. Cell Death and Disease 3, e437.
      Degterev, A., et al. 2005. Nat. Chem. Biol. 1, 112.
      Product Information
      CAS number64419-92-7
      ATP CompetitiveN
      FormLight yellow crystalline solid
      Hill FormulaC₁₂H₁₁N₃OS
      Chemical formulaC₁₂H₁₁N₃OS
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationNecrostatin-1, Inactive Control, CAS 64419-92-7, is a cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) without anti-necroptotic properties.
      Biological Information
      Primary TargetInactive control for Nec-1 (Cat. No. 480065)
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalog Number GTIN
      480066-5MG 04055977201888