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480745 Neuropathiazol

480745
  
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      880090-88-0C₁₉H₁₈N₂O₂S
      Description
      Overview

      This product has been discontinued.





      A cell-permeable thiazole compound that acts as a potent and selective inducer of neuronal differentiation. Shown to induce the differentiation of adult neural progenitor HCN cells into mature neurons (10 µM for 10 days) and competitively suppress astrogliogenesis by LIF/BMP2/FBS in a dose-dependent manner. Reported to be non-cytotoxic and a more selective differentiation inducer than trans-retinoic acid (Cat. No. 554720).
      Catalogue Number480745
      Brand Family Calbiochem®
      SynonymsKHS2
      References
      ReferencesWarashina, M., et al. 2006. Angew. Chem. 45, 591.
      Product Information
      CAS number880090-88-0
      FormWhite solid
      Hill FormulaC₁₉H₁₈N₂O₂S
      Chemical formulaC₁₉H₁₈N₂O₂S
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥96% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      480745 0

      Documentation

      Neuropathiazol SDS

      Title

      Safety Data Sheet (SDS) 

      Neuropathiazol Certificates of Analysis

      TitleLot Number
      480745

      References

      Reference overview
      Warashina, M., et al. 2006. Angew. Chem. 45, 591.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      SynonymsKHS2
      DescriptionA cell-permeable thiazole compound that acts as a potent and selective inducer of neuronal differentiation. Shown to induce the differentiation of adult neural progenitor HCN cells into mature neurons (10 µM for 10 days) and competitively suppress astrogliogenesis by LIF/BMP2/FBS in a dose-dependent manner. Reported to be non-cytotoxic and a more selective differentiation inducer than trans-retinoic acid (Cat. No. 554720).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number880090-88-0
      Chemical formulaC₁₉H₁₈N₂O₂S
      Structure formulaStructure formula
      Purity≥96% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Harmful
      ReferencesWarashina, M., et al. 2006. Angew. Chem. 45, 591.