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459616 Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem

Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: PP1, PP2A
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459616
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
155716-06-6C₄₄H₆₇O₁₃ · NH₄

Pricing & Availability

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459616-25UG
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      Description
      OverviewWater-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
      Catalogue Number459616
      Brand Family Calbiochem®
      References
      ReferencesGjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
      Kiguchi, K., et al. 1994. Cell Growth Differentiation 5, 995.
      Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
      Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
      Kreienbuhl, P., et al. 1992. Blood 80, 2911.
      Normura, M., et al. 1992. Biochemistry 31, 11915.
      Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
      Tada, T., et al. 1992. Immunopharmacol. 24, 17.
      Cohen, P., et al. 1990. Trends Biochem. Sci. 15, 98.
      Cohen, P., et al. 1989. Annu. Rev. Biochem. 58, 453.
      Cohen, P., and Cohen, P.T.W. 1989. J. Biol. Chem. 264, 21435.
      Haystead, T.A.J., et al. 1989. Nature 337, 78.
      Product Information
      CAS number155716-06-6
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₄₄H₆₇O₁₃ · NH₄
      Chemical formulaC₄₄H₆₇O₁₃ · NH₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPP1, PP2A
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 23/24/25-38

      Toxic by inhalation, in contact with skin and if swallowed.
      Irritating to skin.
      S PhraseS: 22-26-36/37/39-45

      Do not breathe dust.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      459616-25UG 04055977204285

      Documentation

      Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      459616

      References

      Reference overview
      Gjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
      Kiguchi, K., et al. 1994. Cell Growth Differentiation 5, 995.
      Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
      Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
      Kreienbuhl, P., et al. 1992. Blood 80, 2911.
      Normura, M., et al. 1992. Biochemistry 31, 11915.
      Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
      Tada, T., et al. 1992. Immunopharmacol. 24, 17.
      Cohen, P., et al. 1990. Trends Biochem. Sci. 15, 98.
      Cohen, P., et al. 1989. Annu. Rev. Biochem. 58, 453.
      Cohen, P., and Cohen, P.T.W. 1989. J. Biol. Chem. 264, 21435.
      Haystead, T.A.J., et al. 1989. Nature 337, 78.

      Brochure

      Title
      Protein Phosphatases Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision09-March-2016 JSW
      DescriptionWater-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
      FormWhite solid
      CAS number155716-06-6
      Chemical formulaC₄₄H₆₇O₁₃ · NH₄
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (20 mg/ml), Ethanol (20 mg/ml), or H₂O (1 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Toxic
      ReferencesGjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
      Kiguchi, K., et al. 1994. Cell Growth Differentiation 5, 995.
      Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
      Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
      Kreienbuhl, P., et al. 1992. Blood 80, 2911.
      Normura, M., et al. 1992. Biochemistry 31, 11915.
      Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
      Tada, T., et al. 1992. Immunopharmacol. 24, 17.
      Cohen, P., et al. 1990. Trends Biochem. Sci. 15, 98.
      Cohen, P., et al. 1989. Annu. Rev. Biochem. 58, 453.
      Cohen, P., and Cohen, P.T.W. 1989. J. Biol. Chem. 264, 21435.
      Haystead, T.A.J., et al. 1989. Nature 337, 78.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Protein Phosphatase Inhibitors