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100482 Periodic acid solution 0.5%

for the PAS reaction for the detection of aldehyde and mucosubstances in microscopy

Periodic acid solution 0.5% MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
100482
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      Description
      Catalogue Number100482
      DescriptionPeriodic acid solution 0.5%
      OverviewThe Periodic acid solution 0.5% for the PAS reaction(periodic acid Schiff) for the detection of aldehyde and mucosubstances in microscopy, is a ready to use solution used for the detection of mucopolysaccharides, glycogen, muco- and glycoproteins, glyco-, phospholipids, basal membranes and collagen. The material is treated with periodic acid creating aldehyde groups which react with Schiff's reagent and give a bright red color reaction, thus the nuclei appear blue.
      In the PAS reaction, the histological specimen material is first treated with periodic acid, resulting in the oxidation of the 1,2-glycols into aldehyde groups. The addition of Schiff’s reagent (fuchsin-sulfuric acid)(Cat.no. 109033) in the second step causes the aldehydes to react to form a brilliant red color. In the end result, the PAS reaction yields a specific color reaction with unsubstituted polysaccharides, neutral mucopolysaccharides, muco- and glycoproteins, and glyco- and phospholipids.
      The PAS reaction can be further combined with the Alcian blue staining method to detect mucosubstances (glycosaminoglycans).
      It is an IVD / CE registered & certified product that can be applied in clinical diagnostics due to its excellent quality. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
      References
      Product Information
      HS Code2811 19 80
      Quality LevelMQ400
      Applications
      Applicationfor the PAS reaction for the detection of aldehyde and mucosubstances in microscopy
      Biological Information
      Physicochemical Information
      Density1.002 g/cm3 (20 °C)
      pH value2.1 (H₂O)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Hazard Statement(s)H412: Harmful to aquatic life with long lasting effects.
      Precautionary Statement(s)P273: Avoid release to the environment.
      P501: Dispose of contents/ container to an approved waste disposal plant.
      Storage class10 - 13 Other liquids and solids
      WGKWGK 2 obviously hazardous to water
      Disposal12
      Inorganic acids and anhydrides thereof should first be diluted or hydrolyzed by stirring carefully into ice water and then neutralized (protective gloves, fume cupboard!) with sodium hydroxide solution (Cat. No. 105587). Before filling into container D, check the pH with pH universal indicator strips (Cat. No. 109535). Fuming sulfuric acid should be carefully stirred dropwise into 40 % sulfuric acid (Cat. No. 109286). Ensure that plenty of ice is available for cooling! When sufficiently cool, treat the highly concentrated sulfuric acid as described above. Analogous to this procedure, other anhydrides can be converted into their corresponding acids. Acid gases (e.g. hydrogen halide, chlorine, phosgene, sulfur dioxide) can be introduced into dilute sodium hydroxide solution and after neutralization disposed of in container D.
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +15°C to +25°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDKein Gefahrgut
      Declaration (transport by air) IATA-DGRNo Dangerous Good
      Declaration (transport by sea) IMDG-CodeNo Dangerous Good
      Supplemental Information
      Specifications
      Nucleiblue
      Polysaccharidespurple
      Glycogenpurple
      Neutral mucopolysaccharidespurple
      Mucoproteinspurple
      Glycoproteinspurple
      Glycolipidspurple
      Phospholipidspurple
      Basement membranepurple
      Collagenpurple
      Global Trade Item Number
      Catalog Number GTIN
      1004821000 04022536706726