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557303 Rifampicin - CAS 13292-46-1 - Calbiochem

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Rifampicin - CAS 13292-46-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Rifampin, 3-(4-Methylpiperazinyliminomethyl)rifamycin SV

Primary Target: DNA-dependent RNA polymerase in bacteria
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557303
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
13292-46-1C₄₃H₅₈N₄O₁₂

Pricing & Availability

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557303-1GM
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      		 1 gm
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      557303-5GM
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          		 Plastic ampoule 5 gm
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          Description
          OverviewAntibiotic that specifically inhibits DNA-dependent RNA polymerase in bacteria by forming an inactive complex. Does not affect mammalian RNA polymerase. Inhibits transcription by preventing the initial transcription complex from entering the elongation mode.
          Catalogue Number557303
          Brand Family Calbiochem®
          SynonymsRifampin, 3-(4-Methylpiperazinyliminomethyl)rifamycin SV
          References
          ReferencesJin, D.J. and Turnbough, Jr., C.L. 1994. J. Mol. Biol. 236, 72.
          Levin, M.E. and Hatfull, G.F. 1993. Mol. Microbiol. 8, 277.
          Wehrli, W., et al. 1968. Proc. Natl. Acad. Sci. USA 61, 667.
          Product Information
          CAS number13292-46-1
          FormBrownish-red to brick-red powder
          Hill FormulaC₄₃H₅₈N₄O₁₂
          Chemical formulaC₄₃H₅₈N₄O₁₂
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetDNA-dependent RNA polymerase in bacteria
          Purity≥97% by Assay
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSVJ7000000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful & Carcinogenic / Teratogenic
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 2 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalog Number GTIN
          557303-1GM 04055977267907
          557303-5GM 07790788051488

          Documentation

          Rifampicin - CAS 13292-46-1 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Rifampicin - CAS 13292-46-1 - Calbiochem Certificates of Analysis

          TitleLot Number
          557303

          References

          Reference overview
          Jin, D.J. and Turnbough, Jr., C.L. 1994. J. Mol. Biol. 236, 72.
          Levin, M.E. and Hatfull, G.F. 1993. Mol. Microbiol. 8, 277.
          Wehrli, W., et al. 1968. Proc. Natl. Acad. Sci. USA 61, 667.

          Brochure

          Title
          Antibiotics Profiler
          Overnight Express Autoinduction Systems

          Citations

          Title
        • Asa Flanigan and Jeffrey F. Gardner. (2007) Interaction of the gifsy-1 xis protein with the gifsy-1 attP sequence. Journal of Bacteriology 189, 6303-6311.
          		•
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-February-2019 JSW
          SynonymsRifampin, 3-(4-Methylpiperazinyliminomethyl)rifamycin SV
          DescriptionAntibiotic that specifically inhibits DNA-dependent bacterial RNA polymerase by forming an inactive complex with RNA polymerase. Does not affect mammalian RNA polymerase. Inhibits transcription by preventing the initial transcription complex from entering the elongation mode.
          FormBrownish-red to brick-red powder
          CAS number13292-46-1
          RTECSVJ7000000
          Chemical formulaC₄₃H₅₈N₄O₁₂
          Structure formulaStructure formula
          Purity≥97% by Assay
          SolubilityDMSO (25 mg/ml) or Methanol (25 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 2 months at -20°C.
          Toxicity Harmful & Carcinogenic / Teratogenic
          Merck USA index14, 8216
          ReferencesJin, D.J. and Turnbough, Jr., C.L. 1994. J. Mol. Biol. 236, 72.
          Levin, M.E. and Hatfull, G.F. 1993. Mol. Microbiol. 8, 277.
          Wehrli, W., et al. 1968. Proc. Natl. Acad. Sci. USA 61, 667.
          Citation
        • Asa Flanigan and Jeffrey F. Gardner. (2007) Interaction of the gifsy-1 xis protein with the gifsy-1 attP sequence. Journal of Bacteriology 189, 6303-6311.
          		•