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581500 TEMPOL - CAS 2226-96-2 - Calbiochem

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap.

TEMPOL - CAS 2226-96-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl

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581500
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
2226-96-2C₉H₁₈NO₂

Pricing & Availability

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581500-500MG
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      		 Plastic ampoule 500 mg
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      Description
      OverviewA stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
      Catalogue Number581500
      Brand Family Calbiochem®
      Synonyms4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
      References
      ReferencesGariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
      Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
      Mota-Filipe, H., et al. 1999. Shock 12, 255.
      Product Information
      CAS number2226-96-2
      ATP CompetitiveN
      FormOrange powder or crystals
      Hill FormulaC₉H₁₈NO₂
      Chemical formulaC₉H₁₈NO₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetFree radical scavenger and nitric oxide spin trap
      Purity≥97% by nitrogen content
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSTN8991000
      Safety Information
      R PhraseR: 22-41

      Harmful if swallowed.
      Risk of serious damage to eyes.
      S PhraseS: 39-26

      Wear eye/face protection.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsPrepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      581500-500MG 04055977265620

      Documentation

      TEMPOL - CAS 2226-96-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      TEMPOL - CAS 2226-96-2 - Calbiochem Certificates of Analysis

      TitleLot Number
      581500

      References

      Reference overview
      Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
      Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
      Mota-Filipe, H., et al. 1999. Shock 12, 255.

      Brochure

      Title
      Pathways and Biomarkers of Oxidative Stress
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision29-June-2018 JSW
      Synonyms4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
      DescriptionA stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
      FormOrange powder or crystals
      Intert gas (Yes/No) Packaged under inert gas
      CAS number2226-96-2
      RTECSTN8991000
      Chemical formulaC₉H₁₈NO₂
      Structure formulaStructure formula
      Purity≥97% by nitrogen content
      SolubilityDMSO (5 mg/ml), ethanol, or H₂O
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsPrepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).
      Toxicity Harmful
      ReferencesGariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
      Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
      Mota-Filipe, H., et al. 1999. Shock 12, 255.