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616455 TGF-β1, Human, Recombinant, CHO Cell Line

TGF-β1, Human, Recombinant, CHO Cell Line MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhTGF-β1, Transforming Growth Factor-β1

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      Overview

      Replacement Information

      Key Specifications Table

      Purity
      ≥97% by SDS-PAGE
      Description
      Overview

      This product has been discontinued.



      Recombinant, human transforming growth factor-β1 expressed in CHO cells. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells. Induces the accumulation of extracellular matrix in various diseases.
      Catalogue Number616455
      Brand Family Calbiochem®
      SynonymsrhTGF-β1, Transforming Growth Factor-β1
      References
      ReferencesShibuya, H., et al. 1996. Science 272, 1179.
      Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA 93, 5877.
      Lomo, J., et al. 1995. J. Immunol. 154, 1634.
      Marushige, K., and Marushige, Y. 1995. Anticancer Res. 14, 2419.
      Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.
      Product Information
      FormLyophilized
      FormulationLyophilized from a sterile filtered solution in 50 µg BSA/µg TGF-β1, 35% acetonitrile, 0.1% TFA.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 0.04-0.1 ng/ml
      Purity≥97% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: ≤1 EU/µg TGF-β1
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      616455 0

      Documentation

      TGF-β1, Human, Recombinant, CHO Cell Line SDS

      Title

      Safety Data Sheet (SDS) 

      TGF-β1, Human, Recombinant, CHO Cell Line Certificates of Analysis

      TitleLot Number
      616455

      References

      Reference overview
      Shibuya, H., et al. 1996. Science 272, 1179.
      Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA 93, 5877.
      Lomo, J., et al. 1995. J. Immunol. 154, 1634.
      Marushige, K., and Marushige, Y. 1995. Anticancer Res. 14, 2419.
      Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.

      Brochure

      Title
      TGF-b Signaling: Dual Role in Tumor Suppression and Oncogenesis
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-May-2008 RFH
      SynonymsrhTGF-β1, Transforming Growth Factor-β1
      DescriptionRecombinant, human transforming growth factor-β1 expressed in CHO cells. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells. Induces the accumulation of extracellular matrix in various diseases.
      FormLyophilized
      FormulationLyophilized from a sterile filtered solution in 50 µg BSA/µg TGF-β1, 35% acetonitrile, 0.1% TFA.
      Purity≥97% by SDS-PAGE
      ContaminantsEndotoxin: ≤1 EU/µg TGF-β1
      Biological activityED₅₀ = 0.04-0.1 ng/ml
      SolubilityReconstitute to a concentration ≥1 µg/ml in 4 mM sterile HCl containing ≥0.1% HSA or BSA.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 9572
      ReferencesShibuya, H., et al. 1996. Science 272, 1179.
      Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA 93, 5877.
      Lomo, J., et al. 1995. J. Immunol. 154, 1634.
      Marushige, K., and Marushige, Y. 1995. Anticancer Res. 14, 2419.
      Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.

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      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors