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616365 Transdermal Hormone Delivery Peptide, TD-1

Transdermal Hormone Delivery Peptide, TD-1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: H-ACSSSPSKHCG-OH, Cyclic, TD-1

616365
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      A highly hydrophilic [Cys-Cys] cyclic 11-mer peptide that facilitates transdermal protein drug delivery by creating a transient opening in the skin barrier. Topical coadministration of TD-1 has been shown to enable insulin and human growth hormone to reach systemic circulation in rats in vivo.
      Catalogue Number616365
      Brand Family Calbiochem®
      SynonymsH-ACSSSPSKHCG-OH, Cyclic, TD-1
      References
      ReferencesChen, Y., et al. 2006. Nat. Biotech. 24, 455.
      Product Information
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₄₀H₆₄N₁₄O₁₆S₂
      Chemical formulaC₄₀H₆₄N₁₄O₁₆S₂
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide SequenceH₂N-Ala-Cys²-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys¹⁰-Gly-CO₂H (Cyclic 2—>10)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      616365 0

      Documentation

      Transdermal Hormone Delivery Peptide, TD-1 Certificates of Analysis

      TitleLot Number
      616365

      References

      Reference overview
      Chen, Y., et al. 2006. Nat. Biotech. 24, 455.

      Brochure

      Title
      Biologics 33.2
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      SynonymsH-ACSSSPSKHCG-OH, Cyclic, TD-1
      DescriptionA highly hydrophilic [Cys-Cys] cyclic 11-mer peptide that facilitates transdermal protein drug delivery by creating a transient opening in the skin barrier. Topical coadministration of TD-1 has been shown to enable insulin and human growth hormone to reach systemic circulation in rats in vivo.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₄₀H₆₄N₁₄O₁₆S₂
      Peptide SequenceH₂N-Ala-Cys²-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys¹⁰-Gly-CO₂H (Cyclic 2—>10)
      Purity≥97% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesChen, Y., et al. 2006. Nat. Biotech. 24, 455.