Vantage® A2 Chromatography Columns
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Overview
Specifications
Ordering Information
Documentation
FAQ
| Question | Answer |
|---|---|
| When I buy a column, what do I need to order? | With the exception of the Vantage A columns, all other column types come as a complete assembly. The Moduline Pilot columns include fittings and tube assemblies to connect to the column. Moduline production and engineered columns are supplied with triclamp type fittings only. Tubing and additional fittings can be supplied as optional items. The Vantage S columns include fractional triclamp fittings, tubing is not supplied. When purchasing the Vantage A column, the column stand and the APC-1 (the air pack controller), are purchased separately. The Vantage A column comes with fractional triclamp fittings; tubing is not supplied. For each column there are recommended lists of spare parts. Suggested spares to have on hand for Vantage columns are the DFC Kit (disposable flow cell). |
| What is the pore size of the bed supports for your different style chromatography columns? Are other pore sizes available? | For Moduline columns the standard porosity for the bed supports are 30 micron polyethylene sinter or 10 micron SST mesh. For customer engineered columns stainless steel mesh (Poristar) is available in 20 micron or 10 micron size as well as 30 micron polyethylene sinter. Vantage bed supports are 15 micron polypropylene, other porosities are not available. |
| What is the material of construction of the bed supports? Are other materials available? | For Moduline columns the standard bed supports material are 30 micron polyethylene sinter or 10 micron SST mesh, (Poristar) . For customer engineered columns 30 micron polyethylene sinter as well as 10 or 20 micron stainless steel mesh are available. Vantage bed supports are 15 micron polypropylene. |
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Categories
| Biopharmaceutical Manufacturing > Downstream Processing > Multi-use Processing Systems > Chromatography Columns and Systems > Systems |
In the pharmaceutical-biotechnology industry, these sanitary columns are ideal for:
- Development
- Pilot processes
- Production purification
Vantage® A2 columns are available in a wide range of sizes; can handle up to 7 bar (100 psi) of pressure; and are especially applicable for use with rigid, higher-resolution, chromatography media.
Benefits
- Axial compression – pneumatically-assisted (to support high-resolution chromatography media)
- Size Options – available in a wide range of sizes (to support a wide range of needs)
- Sanitary design – to ensure that regulatory requirements are met
- Easy of operation – easy to pack and unpacking – does not require re-slurring
| VA60 x 500 mm |
VA90 x 500 mm |
Model VA130 x 500 mm |
VA180 x 500 mm |
VA250 x 500 mm |
|
| Tube internal diameter (mm) | 62 | 89 | 127 | 178 | 252 |
| Cross-sectional area (cm²) | 31 | 62 | 125 | 250 | 500 |
| Adjustable bed height (mm) | 0 – 475 | 0 – 465 | 0 – 460 | 0 – 500 | 0 – 475 |
| Adjustable capacity (L) | 0 – 1.5 | 0 – 2.9 | 0 – 5.8 | 0 – 12.5 | 0 – 23.8 |
| Adjustable bed height with extension tube (mm) | 545 – 1030 | 525 – 1005 | 545 – 1025 | 590 – 1100 | 580 – 1085 |
| Adjustable capacity with extension tube (L) | 1.7 – 3.2 | 3.3 – 6.2 | 6.8 – 12.8 | 14.8 – 27.5 | 29.0 – 53.3 |
| Pressure Rating | 2 – 20 °C, 7 bar; 25 °C, 6.2 bar; 30 °C, 5.5 bar 2 – 20 °C, 100 psi; 25 °C, 90 psi; 30 °C, 80 psi |
||||
| Operating temperature | 2 – 30 °C | ||||
| Materials of Construction | All materials in contact with the process steam meet regulatory requirements | ||||
| Wetted Surfaces | |||||
| Column tube: | TPX (Polymethylpentene) | ||||
| Flow cell: | TPX | ||||
| Support mesh: | Polypropylene 15 µm | ||||
| Flow tube: | Polypropylene | ||||
| Zero dead space adjuster seal: | EPDM | ||||
| Ladish® tube/Flow tube seal: | Santoprene® Thermoplastic Elastomer | ||||
| External Surfaces | 316 stainless steel, aluminum bronze, polypropylene and acetal | ||||