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677500 Vinpocetine

677500
  
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      Overview

      Replacement Information
      Description
      OverviewA cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE 1; IC50 = 20 µM). A cerebral vasodilator.
      Catalogue Number677500
      Brand Family Calbiochem®
      References
      ReferencesMolnar-Kimber, K., et al. 1993. Agents Actions 39, C77. Marley, P.D., and Thomson, K.A. 1992. Biochem. Pharmacol. 44, 2105. Yamaki, M., et al. 1992. Am. J. Physiol. 262, F957. Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331. Hagiwara, M., et al. 1984. Biochem. Pharmacol. 33, 453.
      Product Information
      CAS number42971-09-5
      FormWhite solid
      Hill FormulaC₂₂H₂₆N₂O₂
      Chemical formulaC₂₂H₂₆N₂O₂
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetCa2+ -calmodulin-dependent phosphodiesterase
      Primary Target IC<sub>50</sub>20 µM
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSJW4792000
      Safety Information
      R PhraseR: 22

      Harmful if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      677500 0

      Documentation

      Vinpocetine Certificates of Analysis

      TitleLot Number
      677500

      References

      Reference overview
      Molnar-Kimber, K., et al. 1993. Agents Actions 39, C77. Marley, P.D., and Thomson, K.A. 1992. Biochem. Pharmacol. 44, 2105. Yamaki, M., et al. 1992. Am. J. Physiol. 262, F957. Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331. Hagiwara, M., et al. 1984. Biochem. Pharmacol. 33, 453.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-May-2008 RFH
      DescriptionA cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE 1; IC50 = 20 µM). Cerebral vasodilator.
      FormWhite solid
      CAS number42971-09-5
      RTECSJW4792000
      Chemical formulaC₂₂H₂₆N₂O₂
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityAcetone, Ethanol (10 mg/ml) or DMSO (5 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Harmful
      Merck USA index14, 9991
      ReferencesMolnar-Kimber, K., et al. 1993. Agents Actions 39, C77. Marley, P.D., and Thomson, K.A. 1992. Biochem. Pharmacol. 44, 2105. Yamaki, M., et al. 1992. Am. J. Physiol. 262, F957. Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331. Hagiwara, M., et al. 1984. Biochem. Pharmacol. 33, 453.