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506126 p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem

The p38 MAP Kinase Inhibitor, also referenced under CAS 219138-24-6, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one

Primary Target: p38 MAP kinase
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      219138-24-6C₂₀H₁₃ClFN₃O
      Description
      OverviewA potent p38 MAP kinase inhibitor (IC50 = 35 nM).
      Catalogue Number506126
      Brand Family Calbiochem®
      Synonyms2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one
      References
      Referencesde Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.
      Product Information
      CAS number219138-24-6
      ATP CompetitiveN
      FormPale yellow solid
      Hill FormulaC₂₀H₁₃ClFN₃O
      Chemical formulaC₂₀H₁₃ClFN₃O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetp38 MAP kinase
      Primary Target IC<sub>50</sub>35 nM
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      506126 0

      Documentation

      p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      506126

      References

      Reference overview
      de Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.

      Brochure

      Title
      MAPK Pathway Poster ( 750 KB )
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-October-2007 JSW
      Synonyms2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one
      DescriptionA potent p38 MAP kinase inhibitor (IC50 = 35 nM).
      FormPale yellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number219138-24-6
      Chemical formulaC₂₀H₁₃ClFN₃O
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (25 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      Referencesde Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.