Bioburden Reduction and Prefilters for Sterile Filtration

• Milligard® - cellulosic multimedia filters offer the finest prefiltration levels available, providing unsurpassed protection of the final sterilizing filter from premature plugging.
   
• Polysep® II - multimedia filters combine borosilicate glass fiber with mixed esters of cellulose to provide higher retention efficiency for more critical degrees of prefiltration.
   
• Lifegard™ - borosilicate glass microfiber media filters offer increased adsorptive capacities, ideal for deformable particle retention.
   
• Clarigard® - high performance polypropylene depth filters are comprised of fine diameter polypropylene fibers within an optimized graded density structure. The resulting cartridge filter provides superior retention of particulate and bioburden as well as enhanced throughput capacity.
   
• Polygard®-CN - polypropylene filters provide high retention efficiency, high flow rates, and high dirt-holding capacity with a melt-blown medium fabricated in a pleated format.
   
• Polygard®-CR - polypropylene depth filters offer moderately high retention efficiency, high flow rates, and high dirt-holding capacity by virtue of a graded density of concentrically wrapped media.
   
• Polygard®-CT - polypropylene depth filters provide moderate retention efficiency, high flow rates, and high dirt-holding capacity by virtue of their unique density of concentrically wrapped media.

Cartridge Filters are commonly used for larger processes requiring more filtration area and/or lower unit operating cost. Cartridge filters are used in conjunction with stainless steel housings and can safely withstand multiple steam-in-place cycles. MilliporeSigma cartridge filters are robust, strong, and reliable.

• Opticap® XL disposable capsule filters have a unique design to minimize hold-up volume and reduce production losses and are available in a range of sizes for easy scale-up.
   
• Opticap® XLT disposable T-line capsule filters are available with or without a pressure gauge port for ease in monitoring process conditions. The T-line design accommodates series or parallel filtration to match your application needs.
   
• Optiscale® disposable capsule filters provide a convenient small-volume option for process development, screening and scaling.