oxidative stress
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Oxidative Stress Assays | Life Science Research | MilliporeSigma
Oxidative stress is a cellular disorder caused by an excess of free radicals resulting from increased oxidant levels, decreased anti-oxidant amounts, or failure to repair damage induced by reactive oxygen species (ROS). -
Small Molecules for Oxidative Stress Applications | Life Science Research | MilliporeSigma
For modulating oxidative stress, an unstable cellular environment caused by an excess of free radicals, we provide high quality small molecules inhibitors. -
Antibodies for Oxidative Stress Research | Life Science Research | MilliporeSigma
An excess of free radicals causes oxidative stress, an unstable cellular environment that can result from exposure to alcohol, medications, poor nutrition, trauma, cold, toxins, and overexercise. -
Deregulated Nutrient Sensing | Life Science Research | MilliporeSigma
Organisms depend on multiple nutrient sensing pathways to make sure that the cells and tissue obtain just the right amount of necessary nutrients. Metabolic activities can put stress on our cells. Too much activity, and changes in nutrient availability and composition cause cells to age faster. -
Flow Cytometry Kits for Cell Health | Life Science Research | MilliporeSigma
Parameters of cell health include apoptosis, oxidative stress, mitochondrial health, DNA integrity, and cell cycle profile. FlowCellect Kits enables an easier and accurate studies of cell cycle and cell populations. -
Cellular Senescence | Life Science Research | MilliporeSigma
Cellular senescence is the point at which our cells stop dividing and growing due to damage or lack of necessary components. As cells age, they lose their ability to actively divide and start to undergo senescence. -
Mitochondrial Dysfunction | Life Science Research | MilliporeSigma
Mitochondria responsible for generating ATP, but they act as sensors of cellular distress, and are the first parts of the cell to send and respond to cell death signals. Explore how mitochondrial dysfunction affects the aging process in Hallmarks of aging. -
Cell Health Assays for Muse Cell Analyzer | Life Science Research | MilliporeSigma
Confidence in your experimental results starts with knowing the upstream health status of your cells. For any researchers working with cultured or primary cells, confidence in experimental results begins with knowing cell health status. -
Apoptosis Assays for Muse Cell Analyzer | Life Science Research | MilliporeSigma
Muse kits were designed to help researchers not only detect and quantify apoptosis, but to also characterize it by examining phosphatidylserine translocation, mitochondrial membrane potential (??m), and caspase activation.