Chromatography
On-Demand Webinars

Jan. | 2017

• Presenter: Érica A. Souza-Silva, Federal University of
  Rio Grande do Sul, Brazil
• Abstract

  What Does it Cover?

  Given that SPME is an environmentally friendly sample preparation technique, the interest towards its implementation to a variety of applications continues to increase. However, quite often SPME is not utilized to its full potential due to the lack of proper training. In this webinar, we will be focusing on the implementation of SPME methods for food analysis, including optimization of the factors affecting SPME efficiency; special considerations for targeted and non-targeted applications; quantitation in SPME; and novel SPME devices and future directions.

  What will you learn?

  • Introduction to SPME fundamentals
  • How to develop a SPME method for food and beverage analysis: special attention to complex matrices
  • How to perform quantitative SPME (calibration methods and choice of internal standard in SPME)
  • Future directions and development of new SPME devices

  Why should you attend?

  We will be providing the necessary tools for potential and current SPME users wishing to gain a deeper understanding into the SPME method and thus increasing their productivity.

  Who should attend?

  • Chemists responsible for method development, analytical chemists, laboratory supervisors, scientists and industry regulators who are challenged by complex matrices and laborious sample preparation methods
  • Scientists wishing to implement SPME as a quantitative method
  • Professionals in academia and industry working in the areas of food and beverage interested in implementing SPME as a high throughput method to analyse trace-levels of pesticides.

Sept. | 2016

• Presenter: Petra Lewits, Global Product Manager, Thin Layer Chromatography
• Abstract

  This webinar presents today’s possibilities to achieve rapid quantitative results using Thin-Layer-Chromatography (TLC). TLC/HPTLC (High-Performance Thin-Layer-Chromatography) enables the parallel separation of many samples, leading to separation times per samples of seconds with almost no need for time consuming and costly sample preparation.
  
  In addition, the specific visualization of compounds according to their chemical nature with different derivatisation reagents and the combination with Mass Spectrometry enables a correct and precise identification and quantification of compounds in very complex samples. TLC is the most cost-effective method for rapid quantitative results in Food & Beverage supporting a high level of quality and safety on products we eat and drink.

June | 2016

• Presenter: Dr. Patrik Appelblad, Technical Marketing Manager, Applications, Advanced Analytical
• Abstract

  This webinar focus on how it is possible to comply with USP monographs using the guidelines from general chapter <621>, and it discusses how certain methods can be altered. Results are presented from three of the current USP-NF Monograph Methods for dietary supplements: Black pepper, Ginger, and Turmeric powder, where both HPLC and TLC/HPTLC methods are included for identification and composition analysis.

Sept. | 2015

• Presenter: Dr. Patrik Appelblad, Application Team Manager Instrumental Analytics
• Abstract

  This webinar will focus on regulated chromatographic analysis and how methods can be transferred from one type of column to another with the same chemistry but with different backbones and physical properties.
  
  USP monograph methods, originally developed and validated for use with large particle HPLC columns, have been transferred and partially revalidated for use with monolithic columns.
  
  The examples in this webinar will be used to emphasis the new possibilities in changing HPLC methods per chapter 621 in United States Pharmacopeia.

Sept. | 2015

• Presenter: Hans Griesinger, Advanced Analytics, Instrumental Analytics R&D
• Abstract

  This webinar covers tips and tricks for optimizing the coupling of liquid chromatography with mass spectrometry including:

  • General considerations
  • Mobile phase quality and contamination
  • Solvent storage
  • Equipment cleaning
  • Buffers
  • Column bleeding and washing

  Sensitivity, column robustness and lifetime are discussed, using application examples in LC-MS. Additionally, how to correctly analyze dirty samples with LC-MS is explored.

June | 2015

• Presenter: Michael Schultz, Head of Instrumental Analyics R&D
• Abstract

  The surge in interest of coupling thin layer chromatography (TLC) with mass spectrometry (MS) is due to the availability of commercial instruments that make the routine use of this technique possible. By coupling the advantages of TLC, such as the ability to separate many samples in parallel and the high matrix tolerance of this technique with MS, the TLC-MS becomes a powerful tool in the modern analytical environment. Attendees of the webinar will learn which instruments are available, how to ensure reliable results with the technique, and through the presentation of application examples, what additional value the technique can provide.

May | 2015

• Presenter: Patrik Appelblad, Ph.D., Application Team Manager - Instumental Analysis, Advanced Analytics
• Abstract

  Dissolution testing is an integral part of the drug development lifecycle. The goals of dissolution testing change as the drug moves through the different stages of development. The effectiveness of different drug dosage forms relies on the drug dissolving in a predictable manner prior to absorption into the body. It is also important to optimize the drug's bioavailability over time and deviations from expected dissolution profiles mean that treatment could be either ineffective or dangerous to the patient.
  
  In this webinar you will learn about dissolution testing using a few selected formulated small molecule drugs as examples. The application examples follow the current USP 37 - NF32 monographs and are all compliant with USP 38 - NF33 and the given suitability requirements. In addition to the application examples, the important role of filtration will be discussed in relation to dissolution testing, along with an examination of what changes are possible to the monograph methods.
  
  In this webinar you will learn:

  • Basics of dissolution testing using small molecule drugs as examples
  • The role of filtration in dissolution testing
  • What changes are possible to the monograph methods on dissolution testing

April | 2015

• Presenter: Patrik Appelblad, Ph.D., Application Team Manager - Instumental Analysis, Advanced Analytics
• Abstract

  There are a number of important questions that must be considered when analyzing pharma compounds:

  • How do I comply with the requirements in a monograph?
  • Can the method be optimized or changed? Is there a faster technique?
  • Is this the right grade of chemical for the analysis?

  Using examples from four selected blockbuster molecules that have recently come off patent, or will do so by 2016, this webinar presents details of updated monograph methods describing HPLC, FTIR, Karl Fischer Titration, AAS and ICP methods and we demonstrate how state-of-the-art products simplify analysis of different types of drugs. You will also receive up-to-date information about the United States Pharmacopeia (USP) and National Formulary (NF), including upcoming changes.
  
  This webinar is for anybody who is analysing pharma compounds and is interested in up-to-date information about the United States Pharmacopeia (USP) and National Formula (NF) including upcoming changes

April | 2015

• Presenter: Dr. Egidijus Machtejevas, Senior Product Manager INstrument Analytics, HPLC, Lab Solutions, Advanced Analytics
• Abstract

  Matrix rich samples such as creams, lotions and lipsticks present analytical challenges.
  
  Monolithic silica columns can be of great benefit when dealing with samples like these. In contrast to conventional particle-packed columns, monolithic silica columns are made of a continuous piece of high purity porous silica. High permeability and porosity of the silica skeleton and the resulting low backpressure allow for more flexible flow rates compared to particulate columns. This enables high throughput and robust analysis without loss of separation efficiency or peak capacity — even for relatively “dirty” samples.
  
  In this web seminar, we will demonstrate the benefits of using monolithic silica columns, illustrating those benefits with the numerous experimental data and detailed application examples on a variety of “creamy” sample types.

Sept. | 2014

• Presenter: Patrik Appelblad, Ph.D., Application Team Manager - Instumental Analysis, Advanced Analytics
• Abstract

  The presentation will introduce strategies/solutions to improve food safety using different chromatographic techniques (sample preparation, HPLC/UHPLC, TLC/HPTLC). Scandals in recent years have clearly proven that better testing is required. Techniques have to be more selective, quicker and with higher sensitivity. The talk will discuss the analytical possibilities from a molecular perspective, thus how it is possible to develop a suitable method using the most appropriate analytical technique. The aim with the presentation is that the attendees afterwards will consider the molecule(s) first and choose the most suitable technique from that perspective.

June | 2014

• Presenter: Dr. Stephan Altmaier, Head of Application Lab, Instrumentation Analytics
• Abstract

  The webinar covers tips and tricks for optimizing your coupling liquid chromatography with Mass Spectrometry including:

  • General considerations
  • Mobile phase quality and contamination
  • Solvent storage
  • Equipment cleaning
  • Buffers
  • Column bleeding and washing

  Sensitivity, column robustness and lifetime are discussed, using application examples in LC-MS. Additionally, how to correctly analyze dirty samples with LC-MS is explored.