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03-0125-01 SMC™ Mouse IL-17F Discovery Immunoassay Kit

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03-0125-01
96 well assay  
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      Overview

      Replacement Information

      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey Applications
      IL-17F MSingle Molecule Counting (SMC®)
      Description
      Catalogue Number03-0125-01
      Trade Name
      • SMC®
      DescriptionSMC™ Mouse IL-17F Discovery Immunoassay Kit
      OverviewThe SMC™ Mouse IL-17F Discovery Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology.
      Background InformationInterleukin-17F (IL-17F) is a member of a group of cytokines called the IL-17 family. Other members in the family include IL-17A, IL-17B, IL-17C and IL-17E (IL-17E is also known as IL-25). IL-17F is involved in mediating pro-inflammatory responses by inducing the production of many other cytokines, chemokines, and prostaglandins from many cell types. The increased expression of chemokines attracts other cells, including neutrophils. IL-17F has many physiological functions, such as airway remodeling. As a result of these roles, the IL-17 family has been linked to many immune/autoimmune related diseases, including rheumatoid arthritis (RA), asthma, allergic responses, lupus, allograft rejection and anti-tumor immunity.
      References
      Product Information
      Components
      • Assay Buffer
      • Mouse IL-17F Coating Antibody
      • Assay Plate
      • 10X PBS
      • Blocking Buffer
      • Standard Diluent
      • Mouse IL-17F Detection Antibody
      • Mouse IL-17F Standard
      • SMC™ Mouse IL-17F Immunoassay Kit Instructions
      • 10X Wash Buffer
      • Buffer C
      • Elution Buffer B
      Precision, %
      • Low-end CV% Range: 3-9%
      • Low-end CV% Average: 5%
      Quality LevelMQ200
      Applications
      ApplicationThe sensitivity of Single Molecule Counting (SMC™) technology gives the SMC™ Mouse IL-17F Discovery Immunoassay unparalleled performance in the quantification of IL-17F in mouse serum.
      Key Applications
      • Single Molecule Counting (SMC®)
      Biological Information
      Species Reactivity
      • Mouse
      Analytes Available
      • IL-17F
      Accuracy
      • Minimum of 10 samples spiked with acceptable recovery between 80-120%.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96 well assay
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      03-0125-01 04055977317688

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      Categories

      Life Science Research > Antibodies and Assays > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits
      Life Science Research > Protein Detection and Quantification > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits