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662015 U18666A - CAS 3039-71-2 - Calbiochem

A cell-permeable, amphiphilic amino-steroid that alters intracellular membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol.

U18666A - CAS 3039-71-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3β-(2-Diethylaminoethoxy)androst-5-en-17-one, HCl

Primary Target: Activity of δ8-sterol isomerase
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662015
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
3039-71-2C₂₅H₄₁NO₂ • HCl

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      Description
      OverviewA cell-permeable, amphiphilic amino-steroid that alters intracellular membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol, presumably via its inhibitory effect on 2,3-oxidosqualene-lanosterol cyclase activity. Also reported to inhibit the activity of Δ8-sterol isomerase.
      Catalogue Number662015
      Brand Family Calbiochem®
      Synonyms3β-(2-Diethylaminoethoxy)androst-5-en-17-one, HCl
      References
      ReferencesHall, A.M., et al. 2003. Pigment Cell Res. 16, 149.
      Kobayashi, T., et al. 1998. Nature 392, 193.
      Liscum, L. and Faust, J.R., 1989. J. Biol. Chem. 264, 11796.
      Sexton, R.C., et al. 1983. Biochemistry 22, 5687.
      Bierkamper, G.G. and Cenedella, R.J., 1978. Brain Res. 150, 343.
      Product Information
      CAS number3039-71-2
      ATP CompetitiveN
      FormLyophilized white solid
      Hill FormulaC₂₅H₄₁NO₂ • HCl
      Chemical formulaC₂₅H₄₁NO₂ • HCl
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetActivity of δ8-sterol isomerase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      662015-10MG 04055977261042

      Documentation

      U18666A - CAS 3039-71-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      U18666A - CAS 3039-71-2 - Calbiochem Certificates of Analysis

      TitleLot Number
      662015

      References

      Reference overview
      Hall, A.M., et al. 2003. Pigment Cell Res. 16, 149.
      Kobayashi, T., et al. 1998. Nature 392, 193.
      Liscum, L. and Faust, J.R., 1989. J. Biol. Chem. 264, 11796.
      Sexton, R.C., et al. 1983. Biochemistry 22, 5687.
      Bierkamper, G.G. and Cenedella, R.J., 1978. Brain Res. 150, 343.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-June-2017 JSW
      Synonyms3β-(2-Diethylaminoethoxy)androst-5-en-17-one, HCl
      DescriptionA cell-permeable, amphiphilic amino-steroid that alters intracelluar membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol. Reported to exert its effects via the inhibition of 2,3-oxidosqualene-lanosterol cyclase activity. Also reported to inhibit the activity of Δ8-sterol isomerase.
      FormLyophilized white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number3039-71-2
      Chemical formulaC₂₅H₄₁NO₂ • HCl
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityH₂O (10 mg/ml)
      Storage +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHall, A.M., et al. 2003. Pigment Cell Res. 16, 149.
      Kobayashi, T., et al. 1998. Nature 392, 193.
      Liscum, L. and Faust, J.R., 1989. J. Biol. Chem. 264, 11796.
      Sexton, R.C., et al. 1983. Biochemistry 22, 5687.
      Bierkamper, G.G. and Cenedella, R.J., 1978. Brain Res. 150, 343.