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AB9452 Anti-Muscarinic Acetylcholine Receptor M2 Antibody

Detect Muscarinic Acetylcholine Receptor M2 using this Anti-Muscarinic Acetylcholine Receptor M2 Antibody validated for use in IH(P).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurotransmitters & Receptors Gene Symbol: CHRM2, MGC120006, FLJ43243, MGC120007, HM2 UniProt Number: P08172
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AB9452
50 µg  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9452
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Muscarinic Acetylcholine Receptor M2 Antibody
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Muscarinic Acetylcholine Receptor M2 using this Anti-Muscarinic Acetylcholine Receptor M2 Antibody validated for use in IH(P).
      Key Applications
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry on formalin-fixed, paraffin-embedded tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the 3rd cytoplasmic domain of human Muscarinic Acetylcholine Receptor M2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Muscarinic Acetylcholine Receptor M2.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
      Gene Symbol
      • CHRM2
      • MGC120006
      • FLJ43243
      • MGC120007
      • HM2
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P08172 # The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.
      SIZE: 466 amino acids; 51715 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      SIMILARITY: SwissProt: P08172 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      AB9452 04053252733482

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies