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23-052M Hsp70 Protein, 250 µg

Full length, recombinant human Hsp70. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.

Hsp70 Protein, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Enzyme Assays
23-052M
250 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesCascade Component
      Enzyme AssaysHuman Substrate
      Description
      Catalogue Number23-052M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionHsp70 Protein, 250 µg
      Alternate Names
      • Heat shock 70 kDa protein 1A/1B
      • HSPA1A
      • HSPA1B
      Background InformationHsp70 proteins are central components of the cellular network of molecular chaperones. They assist in a wide range of processes, including the folding and assembly of newly synthesized proteins, refolding of misfolded and aggregated proteins, membrane translocation of organellar and secretory proteins, and control of the activity of regulatory proteins. The cellular levels of Hsp70 are thought to be at least partially regulated by the E3 ubiquitin ligase CHIP, which also targets a broad range of Hsp70 chaperone substrates for proteosomal degradation. Consistent with its diverse activities, genetic and biochemical studies have implicated Hsp70 in a range of diseases including cancer, neurodegeneration, allograft rejection and infection.
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationFull length, recombinant human Hsp70. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.
      Key Applications
      • Enzyme Assays
      Biological Information
      Cascade ComponentSubstrate
      Entrez Gene Number
      Purification MethodPurified using immobilized metal affinity chromatography.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size250 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      23-052M 04053252649912

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      Alternative Packsize

      Catalog Number Description  
      23-052 Hsp70 Protein, 10 µg Show Pricing & Availability

      Product Families

      Ubiquitin Proteasome System: Enzymes and Substrates

      Millipore has removed the complexity of Ubiquitination by providing functionally validated enzymes and substrates, making the pathway readily accessible for research and drug discovery.
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      Categories

      Life Science Research > Drug Discovery and Development > Ubiquitin and Proteasome Screening > Ubiquitination Substrates
      Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Ubiquitination Substrates