Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
If you have chosen panel analytes and then choose a premix or single plex kit, you will lose that customization.
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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506271
Sigma-AldrichKetanserin Tartrate - CAS 83846-83-7 - Calbiochem
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Description
Overview
A selective 5-HT2A serotonin receptor antagonist with weak adrenergic receptor blocking properties. Strong affinity for 5-HT2AR (Ki = 1.49 nM) relative to other family members like 5-HT2BR (Ki = 740 nM) and 5-HT2CR (Ki = 59 nM). Often used in conjunction with SB 206553 to distinguish 5-HT2AR and 5-HT2CR activity.
Catalogue Number
506271
Brand Family
Calbiochem®
Synonyms
5-HT2A Serotonin Receptor Antagonist, Ketanserin, R 41 468
References
References
Ros, R. et al. 2013. PNAS.110, 348. Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol.370, 114. Aloyo, V. J. and Harvey, J. A. 2000. Eur. J. Pharmacol.406, 163. Leysen, J. E. et al. 1981. Life Sci.28, 1015.
If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number
GTIN
5.06271.0001
04055977243192
Documentation
Ketanserin Tartrate - CAS 83846-83-7 - Calbiochem SDS
Ros, R. et al. 2013. PNAS.110, 348. Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol.370, 114. Aloyo, V. J. and Harvey, J. A. 2000. Eur. J. Pharmacol.406, 163. Leysen, J. E. et al. 1981. Life Sci.28, 1015.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
27-September-2013 JSW
Synonyms
5-HT2A Serotonin Receptor Antagonist, Ketanserin, R 41 468
Description
A selective 5-HT2A serotonin receptor antagonist with weak adrenergic receptor blocking properties. Strong affinity for 5-HT2AR (Ki = 1.49 nM) relative to other family members like 5-HT2BR (Ki = 740 nM) and 5-HT2CR (Ki = 59 nM). Often used in conjunction with SB 206553 to distinguish 5-HT2AR and 5-HT2CR activity.
Form
White solid
CAS number
83846-83-7
Chemical formula
C₂₂H₂₂FN₃O₃·C₄H₆O₆
Structure formula
Purity
≥97% by HPLC
Solubility
DMSO
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Toxic
References
Ros, R. et al. 2013. PNAS.110, 348. Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol.370, 114. Aloyo, V. J. and Harvey, J. A. 2000. Eur. J. Pharmacol.406, 163. Leysen, J. E. et al. 1981. Life Sci.28, 1015.
