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480005 NDSB-201 - CAS 15471-17-7 - Calbiochem

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.

NDSB-201 - CAS 15471-17-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3-(1-Pyridino)-1-propane Sulfonate

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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
15471-17-7C₈H₁₁NO₃S

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          Description
          OverviewA non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.
          Catalogue Number480005
          Brand Family Calbiochem®
          Synonyms3-(1-Pyridino)-1-propane Sulfonate
          References
          ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
          Vuillard, L., et al. 1995. Biochem. J. 305, 337.
          Product Information
          CAS number15471-17-7
          FormWhite powder
          Hill FormulaC₈H₁₁NO₃S
          Chemical formulaC₈H₁₁NO₃S
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥99% by titration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +15°C to +30°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalog Number GTIN
          480005-250GM 04055977201789
          480005-25GM 04055977201772

          Documentation

          NDSB-201 - CAS 15471-17-7 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          NDSB-201 - CAS 15471-17-7 - Calbiochem Certificates of Analysis

          TitleLot Number
          480005

          References

          Reference overview
          Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
          Vuillard, L., et al. 1995. Biochem. J. 305, 337.

          Certificates

          Title

          Brochure

          Title
          Detergents Booklet
          Protein Purification and Detection Tools

          Citations

          Title
        • Leslie Lobel, et al. (2002) Bacterial expression of a natively folded extracellular domain fusion protein of the hFSH receptor in the cytoplasm of Escherichia coli. Protein Expression and Purification 25, 124-133.
          		•
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-February-2008 JSW
          Synonyms3-(1-Pyridino)-1-propane Sulfonate
          DescriptionA member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb significantly in the near UV range. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis.
          FormWhite powder
          CAS number15471-17-7
          Chemical formulaC₈H₁₁NO₃S
          Structure formulaStructure formula
          Purity≥99% by titration
          SolubilityH₂O (50 mg/ml)
          Storage +15°C to +30°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.
          Toxicity Irritant
          ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
          Vuillard, L., et al. 1995. Biochem. J. 305, 337.
          Citation
        • Leslie Lobel, et al. (2002) Bacterial expression of a natively folded extracellular domain fusion protein of the hFSH receptor in the cytoplasm of Escherichia coli. Protein Expression and Purification 25, 124-133.
          		•

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          Categories

          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Detergents > Non-Detergent Sulfobetaines