Millipore Sigma Vibrant Logo

108386 Tris(hydroxymethyl)aminomethane

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1201-064-4C₄H₁₁NO₃H₂NC(CH₂OH)₃121.14 g/molPh Eur,BP,ChP,JPC,USP

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
1.08386.1000
Retrieving availability...
Limited Availability
Limited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Plastic bottle 1 kg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      1083865000
      Retrieving availability...
      Limited Availability
Limited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Plastic bottle 5 kg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          1083869013
          Retrieving availability...
          Limited Availability
Limited Availability
          Stocked 
          Discontinued
          Limited Quantities Available
          Available
            Remaining : Will advise
              Remaining : Will advise
              Will advise
              Contact Customer Service
              Contact Customer Service

              Bucket, plastic 12 kg
              Retrieving price...
              Price could not be retrieved
              Minimum Quantity is a multiple of
              Maximum Quantity is
              Upon Order Completion More Information
              You Saved ()
               
              Request Pricing
              1083869025
              Retrieving availability...
              Limited Availability
Limited Availability
              Stocked 
              Discontinued
              Limited Quantities Available
              Available
                Remaining : Will advise
                  Remaining : Will advise
                  Will advise
                  Contact Customer Service
                  Contact Customer Service

                  25 kg
                  Retrieving price...
                  Price could not be retrieved
                  Minimum Quantity is a multiple of
                  Maximum Quantity is
                  Upon Order Completion More Information
                  You Saved ()
                   
                  Request Pricing
                  Description
                  Catalogue Number108386
                  SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
                  DescriptionTris(hydroxymethyl)aminomethane
                  References
                  Product Information
                  CAS number77-86-1
                  EC number201-064-4
                  GradePh Eur,BP,ChP,JPC,USP
                  Hill FormulaC₄H₁₁NO₃
                  Chemical formulaH₂NC(CH₂OH)₃
                  Molar Mass121.14 g/mol
                  HS Code2922 19 99
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ500
                  Applications
                  Biological Information
                  Physicochemical Information
                  Boiling point219 - 220 °C (13.3 hPa)
                  Density1.32 g/cm3 (20 °C)
                  Melting Point169 °C
                  pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
                  Vapor pressure<0.1 hPa (20 °C)
                  Bulk density840 kg/m3
                  Solubility678 g/l
                  Dimensions
                  Materials Information
                  Toxicological Information
                  LD 50 oralLD50 Rat > 5000 mg/kg
                  LD 50 dermalLD50 Rat > 5000 mg/kg
                  Safety Information according to GHS
                  RTECSTY2900000
                  Storage class10 - 13 Other liquids and solids
                  WGKWGK 1 slightly hazardous to water
                  Disposal3
                  Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageNoTempLimit
                  Packaging Information
                  Transport Information
                  Supplemental Information
                  Specifications
                  Global Trade Item Number
                  Catalog Number GTIN
                  1.08386.1000 04022536103846
                  1083865000 04022536775487
                  1083869013 04027269174378
                  1083869025 04022536103853

                  Documentation

                  Material Qualification Dossier

                  TitleVersion
                  6.0

                  Quality Management Dossier (Open Access)

                  Title

                  Operational Excellence Dossier

                  Title

                  Tris(hydroxymethyl)aminomethane SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Tris(hydroxymethyl)aminomethane Certificates of Analysis

                  Product Number PackagingSpecificationLot Number
                  1.08386.1000 Plastic bottlePDF Specification Document
                  1083865000 Plastic bottlePDF Specification Document
                  1083869013 Bucket, plasticPDF Specification Document
                  1083869025 PDF Specification Document

                  Certificates

                  Title

                  Related Products & Applications

                  Related Products By: Application Facete

                  Related Products By: Brand Facete

                  Categories

                  Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
                  Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
                  Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
                  Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers