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100820 Methenamine silver plating kit acc. to Gomori

for the detection of argent-affine structures in histological tissue

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100820
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      Description
      Catalogue Number100820
      DescriptionMethenamine silver plating kit acc. to Gomori
      OverviewThe Methenamine silver plating kit acc. to Gomori - for the detection of argent-affine structures in histological tissue, is used for human-medical cell diagnosis and serves the purpose of the histological investigation of sample material of human origin, for example histological sections of e. g. the kidney, the intestine, or the liver. The periodic acid Schiff (PAS) reaction is often used for the visualization of basal membranes, fungal elements, or other argentaffin structures in the tissue. However, the Methenamine silver plating acc. to Gomori results in better and richer-in-contrast visualization of these target structures.
      In the first step of the silver plating, the Periodic acid oxidizes the 1,2-glycols in the tissue to aldehydes. Due to the incubation with Methenamin-borat silver nitrate solution, these aldehydes are reduced and in turn are responsible for the reduction of the silver ions to metallic silver. This silver will appear black. The subsequent treatment of the tissue with gold chloride intensifies the staining of the argent-affinic structures and concurrently reduces the background staining, and the washing with sodium thiosulfate solution will remove the excess of silver-gold complexes. Like this, the target structures will exhibit a dark brown to black color and all other structures will be counter-stained with light green SF.
      The package is sufficient for up to 50 applications. This product is registered as IVD and CE marked. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
      References
      Product Information
      HS Code3212 90 90
      Quality LevelMQ400
      Applications
      Applicationfor the detection of argent-affine structures in histological tissue
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Pictogram(s)
      Hazard Pictogram(s)
      Hazard Statement(s)H315: Causes skin irritation.
      H317: May cause an allergic skin reaction.
      H319: Causes serious eye irritation.
      H360FD: May damage fertility. May damage the unborn child.
      H373: May cause damage to organs through prolonged or repeated exposure if swallowed.
      H410: Very toxic to aquatic life with long lasting effects.
      Precautionary Statement(s)P202: Do not handle until all safety precautions have been read and understood.
      P273: Avoid release to the environment.
      P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
      P302 + P352: IF ON SKIN: Wash with plenty of water.
      P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
      P308 + P313: IF exposed or concerned: Get medical advice/ attention.
      Signal WordDanger
      Storage class6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
      WGKWGK 3 highly hazardous to water
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +15°C to +25°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDUN 3316 Chemie-Testsatz, 9, II
      Declaration (transport by air) IATA-DGRUN 3316 CHEMICAL KIT, 9, II
      Declaration (transport by sea) IMDG-CodeUN 3316 CHEMICAL KIT, 9, II
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      1008200007 04061838824431

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