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14-666M SRPK2 Protein, active, 250 µg

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14-666M
250 µg  Also available in 10 μg size (cat#14-666) and in bulk (cat#14-666-K).
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      Overview

      Replacement Information
      Description
      Catalogue Number14-666M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionSRPK2 Protein, active, 250 µg
      OverviewN-terminal GST-tagged, recombinant, human SRPK2, amino acids 46-end
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, N-terminal GST-tagged, recombinant, human SRPK2, amino acids 46-end, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceExpressed in E. coli
      Entrez Gene Number
      Gene Symbol
      • SRPK2
      • FLJ36101
      • WUGSC:H_RG152G17.1a
      • SFRSK2
      • H_RG152G17.1b
      • H_RG152G17.1a
      Protein TargetSRPK2
      Purification MethodGlutathione-agarose
      Target Sub-FamilyCMGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P78362 # Phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.
      COFACTOR: Magnesium.
      SIZE: 688 amino acids; 77543 Da
      SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
      TISSUE SPECIFICITY: Highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.
      SIMILARITY: SwissProt: P78362 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
      Molecular Weight100kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of SRPKtide (Catalog # 12-532)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-666) and in bulk (cat#14-666-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      14-666M 04053252924651

      Documentation

      Related Products & Applications

      Alternative Packsize

      Catalog Number Description  
      14-666 SRPK2 Protein, active, 10 µg Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases